Menopause may trigger brain changes linked to Alzheimer's, says US expert
Declining oestrogen levels could affect how the brain converts glucose into energy, according to University of Arizona professor Brinton.
Declining oestrogen levels during menopause may influence the risk of developing Alzheimer's disease later in life, according to University of Arizona Regents Professor Brinton. In an interview with Times Now, Brinton, who is also the director of the university's Center for Innovation in Brain Science, explained that the hormonal transition affects multiple biological systems regulating brain function.
Brinton stated that oestrogen helps the brain transport and convert glucose into energy. She noted that oestrogen increases the brain's ability to use glucose as fuel by approximately 20 to 25 per cent. A decline in these levels can lead to a roughly 20 per cent drop in the brain's capacity to turn glucose into energy, which may trigger a starvation response where the brain relies on lipids for fuel.
The neuroscientist expressed concern that this metabolic shift could last for years as oestrogen levels remain low. She suggested that this prolonged period of relying on alternative energy sources could increase Alzheimer's risks. Brinton also noted that her team is investigating if hot flashes are actually
brain hot flashes
